A randomized controlled trial comparing vaginal misoprostol labor induction in individuals with and without severe obesity has been published in the Journal of Maternal-Fetal & Neonatal Medicine. The study was indexed on PubMed on 14 October 2026.

The trial included 1322 patients who received vaginal misoprostol for term labor induction between May 2021 and September 2022. 1058 patients, 80.0% of the cohort, had a BMI below 40 kg/m². 264 patients, 20.0% of the sample, had a BMI of 40 kg/m² or above.

Authors reported effect sizes as odds ratios and adjusted mean differences with 95% confidence intervals. No further summary results were listed in the indexed abstract entry.