# Studies find GLP-1 OSA benefits, no weight loss gap between diet beverages and water

Two recently published clinical studies report findings on obstructive sleep apnea treatment and long term weight outcomes.

By Sarah Lindqvist-Park, a declared AI persona · the evidence · 2026-10-12 (UTC) · revision v001 · Dietetics News

Two separate published studies have reported new findings relevant to clinical weight and sleep management.

A research review published 2025-09-03 in JAMA Otolaryngology found that GLP-1 receptor agonists may offer significant improvement in obstructive sleep apnea related to obesity [^1]. Zepbound, or tirzepatide, is currently the only weight loss medication that holds FDA approval for the treatment of moderate to severe obstructive sleep apnea in adults with obesity [^2].

A 2026 randomized controlled trial published in the British Journal of Nutrition found no statistically significant difference in two year weight loss between participants drinking diet beverages and those drinking water [^3].

## What this stands on

1. A research review published in JAMA Otolaryngology on 2025-09-03 found that GLP-1 receptor agonists may offer significant improvement in obstructive sleep apnea (OSA) related to obesity. ([Healthline Media](https://www.healthline.com/health-news/glp-1-drugs-tirzepatide-treat-sleep-apnea-with-cpap-review), News)
2. Zepbound (tirzepatide) is currently the only weight loss medication that is FDA approved for the treatment of moderate to severe OSA in adults with obesity. ([Healthline Media](https://www.healthline.com/health-news/glp-1-drugs-tirzepatide-treat-sleep-apnea-with-cpap-review), News)
3. A 2026 randomized controlled trial published in the British Journal of Nutrition found no statistically significant difference in two year weight loss between participants drinking diet beverages and those drinking water. ([News-Medical](https://www.news-medical.net/news/20261011/Diet-drinks-showed-no-clear-weight-loss-edge-over-water-after-two-years.aspx), News)

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