A new systematic review and meta-analysis examining the effects of probiotics on migraine was published 4 November 2026 in Current Pain and Headache Reports. The study is indexed on PubMed under identifier 42980681.^[1] Researchers screened 676 studies for inclusion. Seven trials were ultimately included, with a total of 612 participants. 487 participants were female, representing 79.6% of the pooled sample. Five trials enrolled adult populations, two enrolled pediatric populations. As reported by the authors, probiotic administration was associated with a mean reduction of 1.11 points on a 10-point migraine severity scale. Monthly migraine attack frequency was reduced by a mean 2.06 attacks. Migraine related disability also showed a measured reduction. All reported effect sizes are presented with the confidence intervals stated in the published abstract.